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Combined approaches from physics, statistics, and computer science for ab initio protein structure prediction: ex unitate vires (unity is strength)?

Connecting the dots among the amino acid sequence of a protein, its structure, and its function remains a central theme in molecular biology, as it would have many applications in the treatment of illnesses related to misfolding or protein instability. As a result of high-throughput sequencing metho...

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Detalles Bibliográficos
Autores principales: Delarue, Marc, Koehl, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058471/
https://www.ncbi.nlm.nih.gov/pubmed/30079234
http://dx.doi.org/10.12688/f1000research.14870.1