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Novel application of pluronic lecithin organogels (PLOs) for local delivery of synergistic combination of docetaxel and cisplatin to improve therapeutic efficacy against ovarian cancer

The synergistic combination of docetaxel (DTX) and cisplatin (CIS) by local drug delivery with a pluronic lecithin organogel (PLO) to facilitate high drug concentrations at tumor sites and less nonspecific distribution to normal organs is thought to be beneficial in chemotherapy. In this study, usin...

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Detalles Bibliográficos
Autores principales: Chang, Chia-En, Hsieh, Chien-Ming, Chen, Ling-Chun, Su, Chia-Yu, Liu, Der-Zen, Jhan, Hua-Jing, Ho, Hsiu-O, Sheu, Ming-Thau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058476/
https://www.ncbi.nlm.nih.gov/pubmed/29463123
http://dx.doi.org/10.1080/10717544.2018.1440444