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Preparation of a mesoporous silica-based nano-vehicle for dual DOX/CPT pH-triggered delivery

A dual doxorubicin/camptothecin (DOX/CPT) pH-triggered drug delivery mesoporous silica nanoparticle (MSN)-based nano-vehicle has been prepared. In this drug-delivery system (DDS), CPT is loaded inside the pores of the MSNs, while DOX is covalently attached to the surface of an aldehyde-functionalize...

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Detalles Bibliográficos
Autores principales: Llinàs, Maria C., Martínez-Edo, Gabriel, Cascante, Anna, Porcar, Irene, Borrós, Salvador, Sánchez-García, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058477/
https://www.ncbi.nlm.nih.gov/pubmed/29779394
http://dx.doi.org/10.1080/10717544.2018.1472678