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Delivering CRISPR: a review of the challenges and approaches

Gene therapy has long held promise to correct a variety of human diseases and defects. Discovery of the Clustered Regularly-Interspaced Short Palindromic Repeats (CRISPR), the mechanism of the CRISPR-based prokaryotic adaptive immune system (CRISPR-associated system, Cas), and its repurposing into a...

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Detalles Bibliográficos
Autores principales: Lino, Christopher A., Harper, Jason C., Carney, James P., Timlin, Jerilyn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058482/
https://www.ncbi.nlm.nih.gov/pubmed/29801422
http://dx.doi.org/10.1080/10717544.2018.1474964