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In vivo nose-to-brain delivery of the hydrophilic antiviral ribavirin by microparticle agglomerates

Nasal administration has been proposed as a potential approach for the delivery of drugs to the central nervous system. Ribavirin (RBV), an antiviral drug potentially useful to treat viral infections both in humans and animals, has been previously demonstrated to attain several brain compartments af...

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Detalles Bibliográficos
Autores principales: Giuliani, Alessandro, Balducci, Anna Giulia, Zironi, Elisa, Colombo, Gaia, Bortolotti, Fabrizio, Lorenzini, Luca, Galligioni, Viola, Pagliuca, Giampiero, Scagliarini, Alessandra, Calzà, Laura, Sonvico, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058489/
https://www.ncbi.nlm.nih.gov/pubmed/29382237
http://dx.doi.org/10.1080/10717544.2018.1428242