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Dipeptide-modified nanoparticles to facilitate oral docetaxel delivery: new insights into PepT1-mediated targeting strategy

Oligopeptide transporter 1 (PepT1) has been a striking prodrug-designing target. However, the underlying mechanism of PepT1 as a target to facilitate the oral absorption of nanoparticles (NPs) remains unclear. Herein, we modify Poly (lactic-co-glycolic acid) (PLGA) NPs with the conjugates of dipepti...

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Detalles Bibliográficos
Autores principales: Du, Yuqian, Tian, Chutong, Wang, Menglin, Huang, Di, Wei, Wei, Liu, Yan, Li, Lin, Sun, Bingjun, Kou, Longfa, Kan, Qiming, Liu, Kexin, Luo, Cong, Sun, Jin, He, Zhonggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058494/
https://www.ncbi.nlm.nih.gov/pubmed/29890854
http://dx.doi.org/10.1080/10717544.2018.1480675