Preparation of curcumin self-micelle solid dispersion with enhanced bioavailability and cytotoxic activity by mechanochemistry

An amorphous solid dispersion (SD) of curcumin (Cur) with disodium glycyrrhizin (Na(2)GA) was prepared by mechanical ball milling. Curcumin loaded micelles were self-formed by Na(2)GA when SD dissolved in water. The physical properties of Cur SD in solid state were characterized by differential scan...

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Detalles Bibliográficos
Autores principales: Zhang, Qihong, Polyakov, Nikolay E., Chistyachenko, Yulia S., Khvostov, Mikhail V., Frolova, Tatjana S., Tolstikova, Tatjana G., Dushkin, Alexandr V., Su, Weike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058497/
https://www.ncbi.nlm.nih.gov/pubmed/29302995
http://dx.doi.org/10.1080/10717544.2017.1422298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058497/
https://www.ncbi.nlm.nih.gov/pubmed/29302995
http://dx.doi.org/10.1080/10717544.2017.1422298

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