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Preparation of curcumin self-micelle solid dispersion with enhanced bioavailability and cytotoxic activity by mechanochemistry
An amorphous solid dispersion (SD) of curcumin (Cur) with disodium glycyrrhizin (Na(2)GA) was prepared by mechanical ball milling. Curcumin loaded micelles were self-formed by Na(2)GA when SD dissolved in water. The physical properties of Cur SD in solid state were characterized by differential scan...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058497/ https://www.ncbi.nlm.nih.gov/pubmed/29302995 http://dx.doi.org/10.1080/10717544.2017.1422298 |