Localized delivery of therapeutic doxorubicin dose across the canine blood–brain barrier with hyperthermia and temperature sensitive liposomes

Most drugs cannot penetrate the blood–brain barrier (BBB), greatly limiting the use of anti-cancer agents for brain cancer therapy. Temperature sensitive liposomes (TSL) are nanoparticles that rapidly release the contained drug in response to hyperthermia (>40 °C). Since hyperthermia also transie...

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Detalles Bibliográficos
Autores principales: Bredlau, Amy Lee, Motamarry, Anjan, Chen, Chao, McCrackin, M. A., Helke, Kris, Armeson, Kent E., Bynum, Katrina, Broome, Ann-Marie, Haemmerich, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058514/
https://www.ncbi.nlm.nih.gov/pubmed/29688083
http://dx.doi.org/10.1080/10717544.2018.1461280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058514/
https://www.ncbi.nlm.nih.gov/pubmed/29688083
http://dx.doi.org/10.1080/10717544.2018.1461280

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