Bispecific antibodies (anti-mPEG/anti-HER2) for active tumor targeting of docetaxel (DTX)-loaded mPEGylated nanocarriers to enhance the chemotherapeutic efficacy of HER2-overexpressing tumors

Anti-mPEG/anti-human epidermal growth factor receptor 2 (HER2) bispecific antibodies (BsAbs) non-covalently bound to a docetaxel (DTX)-loaded mPEGylated lecithin-stabilized micellar drug delivery system (L(sb)MDDs) were endowed with active targetability to improve the chemotherapeutic efficacy of DT...

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Detalles Bibliográficos
Autores principales: Su, Chia-Yu, Chen, Michael, Chen, Ling-Chun, Ho, Yuan-Soon, Ho, Hsiu-O, Lin, Shyr-Yi, Chuang, Kuo-Hsiang, Sheu, Ming-Thau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058516/
https://www.ncbi.nlm.nih.gov/pubmed/29718725
http://dx.doi.org/10.1080/10717544.2018.1466936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058516/
https://www.ncbi.nlm.nih.gov/pubmed/29718725
http://dx.doi.org/10.1080/10717544.2018.1466936

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