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Modification of translationally controlled tumor protein-derived protein transduction domain for improved intranasal delivery of insulin

Carrier peptides, termed protein transduction domains (PTDs), serve as provide promising vehicles for intranasal delivery of macromolecular drugs. A mutant PTD derived from human translationally controlled tumor protein (TCTP-PTD 13, MIIFRALISHKK) was reported to provide enhanced intranasal delivery...

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Detalles Bibliográficos
Autores principales: Bae, Hae-Duck, Lee, Joohyun, Jun, Kyu-Yeon, Kwon, Youngjoo, Lee, Kyunglim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058520/
https://www.ncbi.nlm.nih.gov/pubmed/29688087
http://dx.doi.org/10.1080/10717544.2018.1464081