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Novel polyethyleneimine-R8-heparin nanogel for high-efficiency gene delivery in vitro and in vivo

Gene therapy is an efficient and promising approach to treat malignant tumors. However, protecting the nucleic acid from degradation in vivo and efficient delivering it into tumor cells remain challenges that require to be addressed before gene therapy could be applied in clinic. In this study, we p...

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Detalles Bibliográficos
Autores principales: Song, Linjiang, Liang, Xiuqi, Yang, Suleixin, Wang, Ning, He, Tao, Wang, Yan, Zhang, Lan, Wu, Qinjie, Gong, Changyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058572/
https://www.ncbi.nlm.nih.gov/pubmed/29265887
http://dx.doi.org/10.1080/10717544.2017.1417512