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Novel polyethyleneimine-R8-heparin nanogel for high-efficiency gene delivery in vitro and in vivo
Gene therapy is an efficient and promising approach to treat malignant tumors. However, protecting the nucleic acid from degradation in vivo and efficient delivering it into tumor cells remain challenges that require to be addressed before gene therapy could be applied in clinic. In this study, we p...
Autores principales: | Song, Linjiang, Liang, Xiuqi, Yang, Suleixin, Wang, Ning, He, Tao, Wang, Yan, Zhang, Lan, Wu, Qinjie, Gong, Changyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058572/ https://www.ncbi.nlm.nih.gov/pubmed/29265887 http://dx.doi.org/10.1080/10717544.2017.1417512 |
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