Regression of prostate tumors after intravenous administration of lactoferrin-bearing polypropylenimine dendriplexes encoding TNF-α, TRAIL, and interleukin-12

The possibility of using gene therapy for the treatment of prostate cancer is limited by the lack of intravenously administered delivery systems able to safely and selectively deliver therapeutic genes to tumors. Given that lactoferrin (Lf) receptors are overexpressed on prostate cancer cells, we hy...

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Detalles Bibliográficos
Autores principales: Altwaijry, Najla, Somani, Sukrut, Parkinson, John A., Tate, Rothwelle J., Keating, Patricia, Warzecha, Monika, Mackenzie, Graeme R., Leung, Hing Y., Dufès, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058574/
https://www.ncbi.nlm.nih.gov/pubmed/29493296
http://dx.doi.org/10.1080/10717544.2018.1440666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058574/
https://www.ncbi.nlm.nih.gov/pubmed/29493296
http://dx.doi.org/10.1080/10717544.2018.1440666

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