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Formulation and in vivo assessment of terconazole-loaded polymeric mixed micelles enriched with Cremophor EL as dual functioning mediator for augmenting physical stability and skin delivery

The aim of the current study was to formulate terconazole (TCZ) loaded polymeric mixed micelles (PMMs) incorporating Cremophor EL as a stabilizer and a penetration enhancer. A 2(3) full factorial design was performed using Design-Expert® software for the optimization of the PMMs which were formulate...

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Detalles Bibliográficos
Autores principales: Abd-Elsalam, Wessam H., El-Zahaby, Sally A., Al-Mahallawi, Abdulaziz M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058577/
https://www.ncbi.nlm.nih.gov/pubmed/29411650
http://dx.doi.org/10.1080/10717544.2018.1436098