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On-target and direct modulation of alloreactive T cells by a nanoparticle carrying MHC alloantigen, regulatory molecules and CD47 in a murine model of alloskin transplantation

Biomimetic nanoparticles have been reported as immune modulators in autoimmune diseases and allograft rejections by numerous researchers. However, most of the therapeutics carrying antigens, toxins or cytokines underlay the mechanism of antigen presentation by cellular uptake of NPs through pinocyto...

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Detalles Bibliográficos
Autores principales: Shahzad, Khawar Ali, Wan, Xin, Zhang, Lei, Pei, Weiya, Zhang, Aifeng, Younis, Muhammad, Wang, Wei, Shen, Chuanlai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058602/
https://www.ncbi.nlm.nih.gov/pubmed/29508634
http://dx.doi.org/10.1080/10717544.2018.1447049