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Folate-targeting annonaceous acetogenins nanosuspensions: significantly enhanced antitumor efficacy in HeLa tumor-bearing mice

Annonaceous acetogenins (ACGs) are one of the most active constituents isolated from Annona species with potent antitumor activity. However, the poor solubility and severe side effect greatly limit their use in clinic. In this study, folic acid (FA) modified annonaceous acetogenins nanosuspensions (...

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Detalles Bibliográficos
Autores principales: Li, Haowen, Li, Yijing, Ao, Hui, Bi, Dongdong, Han, Meihua, Guo, Yifei, Wang, Xiangtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058653/
https://www.ncbi.nlm.nih.gov/pubmed/29608108
http://dx.doi.org/10.1080/10717544.2018.1455761