Estrogen-functionalized liposomes grafted with glutathione-responsive sheddable chotooligosaccharides for the therapy of osteosarcoma

An estrogen (ES)-functionalized cationic liposomal system was developed and exploited for targeted delivery to osteosarcoma. Natural biocompatible chotooligosaccharides (COS, MW2-5 KDa) were covalently tethered to the liposomal surface through a disulfate bond (-SS-) to confer reduction-responsive C...

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Detalles Bibliográficos
Autores principales: Yin, Xuelei, Feng, Shuaishuai, Chi, Yingying, Liu, Jinhu, Sun, Kaoxiang, Guo, Chuanyou, Wu, Zimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058671/
https://www.ncbi.nlm.nih.gov/pubmed/29644882
http://dx.doi.org/10.1080/10717544.2018.1458920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058671/
https://www.ncbi.nlm.nih.gov/pubmed/29644882
http://dx.doi.org/10.1080/10717544.2018.1458920

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