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Cefquinome-loaded microsphere formulations against Klebsiella pneumonia infection during experimental infections
The aim of this study was to prepare cefquinome-loaded polylactic acid microspheres and to evaluate their in vitro and in vivo characteristics and pharmacodynamics for the therapy of pneumonia in a rat model. Microspheres were prepared using a 0.7 mm two-fluid nozzle spray drier in one step resultin...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058672/ https://www.ncbi.nlm.nih.gov/pubmed/29649952 http://dx.doi.org/10.1080/10717544.2018.1461958 |