Gastroretentive raft liquid delivery system as a new approach to release extension for carrier-mediated drug

Gabapentin (GBP), an antiepileptic and anti-neuropathic agent, suffers from short half-life (5–7 h), has narrow absorption window, and is absorbed via carrier-mediated mechanism resulting in frequent dosing, poor compliance, and poor bioavailability (<60%). Moreover, GBP is a freely water-soluble...

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Detalles Bibliográficos
Autores principales: Abouelatta, Samar M., Aboelwafa, Ahmed A., El-Gazayerly, Omaima N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058684/
https://www.ncbi.nlm.nih.gov/pubmed/29792353
http://dx.doi.org/10.1080/10717544.2018.1474969

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058684/
https://www.ncbi.nlm.nih.gov/pubmed/29792353
http://dx.doi.org/10.1080/10717544.2018.1474969

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