Cargando…

α-Conotoxin ImI-modified polymeric micelles as potential nanocarriers for targeted docetaxel delivery to α7-nAChR overexpressed non-small cell lung cancer

A micelle system modified with α-Conotoxin ImI (ImI), a potently antagonist for alpha7 nicotinic acetylcholine receptor (α7-nAChR) previously utilized for targeting breast cancer, was constructed. Its targeting efficiency and cytotoxicity against non-small cell lung cancer (NSCLC) highly expressing...

Descripción completa

Detalles Bibliográficos
Autores principales: Mei, Dong, Zhao, Libo, Chen, Binlong, Zhang, Xiaoyan, Wang, Xiaoling, Yu, Zhiying, Ni, Xin, Zhang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058686/
https://www.ncbi.nlm.nih.gov/pubmed/29426250
http://dx.doi.org/10.1080/10717544.2018.1436097