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α-Conotoxin ImI-modified polymeric micelles as potential nanocarriers for targeted docetaxel delivery to α7-nAChR overexpressed non-small cell lung cancer
A micelle system modified with α-Conotoxin ImI (ImI), a potently antagonist for alpha7 nicotinic acetylcholine receptor (α7-nAChR) previously utilized for targeting breast cancer, was constructed. Its targeting efficiency and cytotoxicity against non-small cell lung cancer (NSCLC) highly expressing...
Autores principales: | Mei, Dong, Zhao, Libo, Chen, Binlong, Zhang, Xiaoyan, Wang, Xiaoling, Yu, Zhiying, Ni, Xin, Zhang, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058686/ https://www.ncbi.nlm.nih.gov/pubmed/29426250 http://dx.doi.org/10.1080/10717544.2018.1436097 |
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