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Pulmonary delivery of influenza vaccine formulations in cotton rats: site of deposition plays a minor role in the protective efficacy against clinical isolate of H1N1pdm virus

Administration of influenza vaccines to the lungs could be an attractive alternative to conventional parenteral administration. In this study, we investigated the deposition site of pulmonary delivered liquid and powder influenza vaccine formulations and its relation to their immunogenicity and prot...

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Detalles Bibliográficos
Autores principales: Bhide, Yoshita, Tomar, Jasmine, Dong, Wei, de Vries-Idema, Jacqueline, Frijlink, Henderik W., Huckriede, Anke, Hinrichs, Wouter L. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058687/
https://www.ncbi.nlm.nih.gov/pubmed/29451040
http://dx.doi.org/10.1080/10717544.2018.1435748