Development of novel bioadhesive granisetron hydrochloride spanlastic gel and insert for brain targeting and study their effects on rats

The aim of this study was to formulate granisetron hydrochloride (GH) spanlastic in mucoadhesive gels and lyophilized inserts for intranasal administration to improve GH bioavailability and brain targeting. Carpapol 934 and HPMC were incorporated in GH spanlastic in nasal gels (GHSpNGs). Gelatin and...

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Detalles Bibliográficos
Autores principales: Abdelmonem, Rehab, el Nabarawi, Mohamed, Attia, Alshaimaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058699/
https://www.ncbi.nlm.nih.gov/pubmed/29228824
http://dx.doi.org/10.1080/10717544.2017.1413447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058699/
https://www.ncbi.nlm.nih.gov/pubmed/29228824
http://dx.doi.org/10.1080/10717544.2017.1413447

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