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Dual-targeting for brain-specific drug delivery: synthesis and biological evaluation

Ibuprofen is one of the most potent non-steroid anti-inflammatory drugs (NSAIDs) and plays an important role in the treatment of neurodegenerative diseases. However, its poor brain penetration and serious side effects at therapeutic doses, has hindered its further application. Thus, it is of great i...

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Detalles Bibliográficos
Autores principales: Yue, Qiming, Peng, Yao, Zhao, Yi, Lu, Runxin, Fu, Qiuyi, Chen, Yang, Yang, Yang, Hai, Li, Guo, Li, Wu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058731/
https://www.ncbi.nlm.nih.gov/pubmed/29382239
http://dx.doi.org/10.1080/10717544.2018.1431978