Cargando…

Dual-targeting for brain-specific drug delivery: synthesis and biological evaluation

Ibuprofen is one of the most potent non-steroid anti-inflammatory drugs (NSAIDs) and plays an important role in the treatment of neurodegenerative diseases. However, its poor brain penetration and serious side effects at therapeutic doses, has hindered its further application. Thus, it is of great i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yue, Qiming, Peng, Yao, Zhao, Yi, Lu, Runxin, Fu, Qiuyi, Chen, Yang, Yang, Yang, Hai, Li, Guo, Li, Wu, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058731/ https://www.ncbi.nlm.nih.gov/pubmed/29382239 http://dx.doi.org/10.1080/10717544.2018.1431978

Ejemplares similares

Synthesis of high drug loading, reactive oxygen species and esterase dual-responsive polymeric micelles for drug delivery
por: Wang, Nan, et al.
Publicado: (2019)

Hydrogen-bond super-amphiphile based drug delivery system: design, synthesis, and biological evaluation
por: Chen, Jiali, et al.
Publicado: (2022)

Synthesis and Characterization of Dual-Sensitive Fluorescent Nanogels for Enhancing Drug Delivery and Tracking Intracellular Drug Delivery
por: Wu, Szu-Yuan, et al.
Publicado: (2017)

Accurate programmed multifunctional nano-missiles for self-promoted deep delivery and synergistic cascade tumor therapy: Tactfully collaborating chemosynthesis with tumor microenvironment remodeling
por: Lu, Runxin, et al.
Publicado: (2022)

Dual-modified natural high density lipoprotein particles for systemic glioma-targeting drug delivery
por: Cui, Lin, et al.
Publicado: (2018)

Synthesis and Characterization of a Novel Dual-Responsive Nanogel for Anticancer Drug Delivery
por: Aminoleslami, Darya, et al.
Publicado: (2022)

Rapid In Situ MRI Traceable Gel-forming Dual-drug Delivery for Synergistic Therapy of Brain Tumor
por: Lin, Feng-Wei, et al.
Publicado: (2017)

Recent advances in drug delivery systems for targeting brain tumors
por: Zhao, Yi, et al.
Publicado: (2023)

Redox dual-stimuli responsive drug delivery systems for improving tumor-targeting ability and reducing adverse side effects
por: Li, Ruirui, et al.
Publicado: (2020)

Organism‐Generated Biological Vesicles In Situ: An Emerging Drug Delivery Strategy
por: Kong, Li, et al.
Publicado: (2022)

Synthesis and modification of ZIF-8 and its application in drug delivery and tumor therapy
por: Wang, Qiuxiang, et al.
Publicado: (2020)

Biological drug and drug delivery-mediated immunotherapy
por: Xiao, Qingqing, et al.
Publicado: (2021)

Synthesis and Biological Evaluation of RGD–Cryptophycin Conjugates for Targeted Drug Delivery
por: Borbély, Adina, et al.
Publicado: (2019)

Gram Scale Synthesis of Dual-Responsive Dendritic Polyglycerol Sulfate as Drug Delivery System
por: Reisbeck, Felix, et al.
Publicado: (2021)

A DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery
por: Ren, Kewei, et al.
Publicado: (2016)

Plant Exosome-like Nanoparticles as Biological Shuttles for Transdermal Drug Delivery
por: Wang, Ye, et al.
Publicado: (2023)

Dual-sensitive chitosan derivative micelles for site-specific drug release in the treatment of chicken coccidiosis
por: Zhang, Xin, et al.
Publicado: (2018)

Synthesis and biological evaluation of lycorine derivatives as dual inhibitors of human acetylcholinesterase and butyrylcholinesterase
por: Wang, Yue-Hu, et al.
Publicado: (2012)

Dual Functionalized Liposomes for Selective Delivery of Poorly Soluble Drugs to Inflamed Brain Regions
por: Giofrè, Sabrina, et al.
Publicado: (2022)

Synthesis of Multi-Functional Nano-Vectors for Target-Specific Drug Delivery
por: Wu, Tzu-Chien, et al.
Publicado: (2021)

Brain-targeted drug delivery by manipulating protein corona functions
por: Zhang, Zui, et al.
Publicado: (2019)

Elaborately Engineering a Self‐Indicating Dual‐Drug Nanoassembly for Site‐Specific Photothermal‐Potentiated Thrombus Penetration and Thrombolysis
por: Zhao, Zhiqiang, et al.
Publicado: (2021)

Synthesis and Biological Evaluation of Liguzinediol Mono- and Dual Ester Prodrugs as Promising Inotropic Agents
por: Zhang, Jing, et al.
Publicado: (2014)

PSMA-Oriented Target Delivery of Novel Anticancer Prodrugs: Design, Synthesis, and Biological Evaluations of Oligopeptide-Camptothecin Conjugates
por: Xu, Bing, et al.
Publicado: (2018)

cmFSM: a scalable CPU-MIC coordinated drug-finding tool by frequent subgraph mining
por: Yang, Shunyun, et al.
Publicado: (2018)

Targeting the Opening of Mitochondrial Permeability Transition Pores Potentiates Nanoparticle Drug Delivery and Mitigates Cancer Metastasis
por: Lin, Xi, et al.
Publicado: (2020)

Pulmonary Delivery of Biological Drugs
por: Liang, Wanling, et al.
Publicado: (2020)

OX26/CTX-conjugated PEGylated liposome as a dual-targeting gene delivery system for brain glioma
por: Yue, Pei-jian, et al.
Publicado: (2014)

Synthesis of graphene quantum dots and their applications in drug delivery
por: Zhao, Changhong, et al.
Publicado: (2020)

Cell-Penetrating Peptides as Valuable Tools for Nose-to-Brain Delivery of Biological Drugs
por: De Martini, Lisa Benedetta, et al.
Publicado: (2023)

Recent advances on cyclodepsipeptides: biologically active compounds for drug research
por: Liu, Si-Xuan, et al.
Publicado: (2023)

A combinational chemo-immune therapy using an enzyme-sensitive nanoplatform for dual-drug delivery to specific sites by cascade targeting
por: He, Yanmei, et al.
Publicado: (2021)

Sequential delivery of dual drugs with nanostructured lipid carriers for improving synergistic tumor treatment effect
por: Xu, Man, et al.
Publicado: (2020)

Nanofibrous bicomponent scaffolds for the dual delivery of NGF and GDNF: controlled release of growth factors and their biological effects
por: Liu, Chaoyu, et al.
Publicado: (2021)

Precise synthesis of sulfur-containing polymers via cooperative dual organocatalysts with high activity
por: Zhang, Cheng-Jian, et al.
Publicado: (2018)

Design, Synthesis and Biological Evaluation of Diosgenin-Amino Acid Derivatives with Dual Functions of Neuroprotection and Angiogenesis
por: Cai, Desheng, et al.
Publicado: (2019)

Synthesis and characterization of multifunctional hybrid-polymeric nanoparticles for drug delivery and multimodal imaging of cancer
por: Tng, Danny Jian Hang, et al.
Publicado: (2015)

Ferroptosis-based drug delivery system as a new therapeutic opportunity for brain tumors
por: Yao, Yansheng, et al.
Publicado: (2023)

Rational drug design, synthesis, and biological evaluation of novel chiral tetrahydronaphthalene-fused spirooxindole as MDM2-CDK4 dual inhibitor against glioblastoma
por: Wang, Biao, et al.
Publicado: (2020)

pH and lipase-responsive nanocarrier-mediated dual drug delivery system to treat periodontitis in diabetic rats
por: Wang, Lu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vdlolupph5ethbnbvlfcj1mh7e