Effects of 3-Tetrazolyl Methyl-3-Hydroxy-Oxindole Hybrid (THOH) on Cell Proliferation, Apoptosis, and G2/M Cell Cycle Arrest Occurs by Targeting Platelet-Derived Growth Factor D (PDGF-D) and the MEK/ERK Signaling Pathway in Human Lung Cell Lines SK-LU-1, A549, and A-427

BACKGROUND: The aim of this study was to evaluate the effects of 3-tetrazolyl methyl-3-hydroxy-oxindole hybrid (THOH) on cell proliferation, apoptosis, and the cell cycle in human lung cancer cell lines SK-LU-1, A549, and A-427, and the normal lung fibroblast cell line, MRC-5, in vitro. MATERIAL/MET...

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Detalles Bibliográficos
Autores principales: Li, Peng, Zhang, Zhiqiang, Zhang, Feng, Zhou, Hongling, Sun, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058735/
https://www.ncbi.nlm.nih.gov/pubmed/29961751
http://dx.doi.org/10.12659/MSM.909125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058735/
https://www.ncbi.nlm.nih.gov/pubmed/29961751
http://dx.doi.org/10.12659/MSM.909125

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