Cargando…
Fit αβ T-cell receptor suppresses leukemogenesis of Pten-deficient thymocytes
Signaling through the αβT cell receptor (TCR) is a crucial determinant of T-cell fate and can induce two opposite outcomes during thymocyte development: cell death or survival and differentiation. To date, the role played by T-cell receptor in the oncogenic transformation of developing T cells remai...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058769/ https://www.ncbi.nlm.nih.gov/pubmed/29567770 http://dx.doi.org/10.3324/haematol.2018.188359 |