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Fit αβ T-cell receptor suppresses leukemogenesis of Pten-deficient thymocytes
Signaling through the αβT cell receptor (TCR) is a crucial determinant of T-cell fate and can induce two opposite outcomes during thymocyte development: cell death or survival and differentiation. To date, the role played by T-cell receptor in the oncogenic transformation of developing T cells remai...
Autores principales: | Gon, Stéphanie, Loosveld, Marie, Crouzet, Thomas, Potier, Delphine, Bonnet, Mélanie, Morin, Stéphanie O., Michel, Gérard, Vey, Norbert, Nunès, Jacques A., Malissen, Bernard, Roncagalli, Romain, Nadel, Bertrand, Payet-Bornet, Dominique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058769/ https://www.ncbi.nlm.nih.gov/pubmed/29567770 http://dx.doi.org/10.3324/haematol.2018.188359 |
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