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DNA polymerase ν gene expression influences fludarabine resistance in chronic lymphocytic leukemia independently of p53 status

Alteration in the DNA replication, repair or recombination processes is a highly relevant mechanism of genomic instability. Despite genomic aberrations manifested in hematologic malignancies, such a defect as a source of biomarkers has been underexplored. Here, we investigated the prognostic value o...

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Detalles Bibliográficos
Autores principales: Grgurevic, Srdana, Montilla-Perez, Patricia, Bradbury, Alice, Gilhodes, Julia, Queille, Sophie, Pelofy, Sandrine, Bancaud, Aurélien, Filleron, Thomas, Ysebaert, Loïc, Récher, Christian, Laurent, Guy, Fournié, Jean-Jacques, Cazaux, Christophe, Quillet-Mary, Anne, Hoffmann, Jean-Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058778/
https://www.ncbi.nlm.nih.gov/pubmed/29567785
http://dx.doi.org/10.3324/haematol.2017.174243