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DNA polymerase ν gene expression influences fludarabine resistance in chronic lymphocytic leukemia independently of p53 status
Alteration in the DNA replication, repair or recombination processes is a highly relevant mechanism of genomic instability. Despite genomic aberrations manifested in hematologic malignancies, such a defect as a source of biomarkers has been underexplored. Here, we investigated the prognostic value o...
Autores principales: | Grgurevic, Srdana, Montilla-Perez, Patricia, Bradbury, Alice, Gilhodes, Julia, Queille, Sophie, Pelofy, Sandrine, Bancaud, Aurélien, Filleron, Thomas, Ysebaert, Loïc, Récher, Christian, Laurent, Guy, Fournié, Jean-Jacques, Cazaux, Christophe, Quillet-Mary, Anne, Hoffmann, Jean-Sébastien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058778/ https://www.ncbi.nlm.nih.gov/pubmed/29567785 http://dx.doi.org/10.3324/haematol.2017.174243 |
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