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Leukemia reconstitution in vivo is driven by cells in early cell cycle and low metabolic state
In contrast to well-established hierarchical concepts of tumor stem cells, leukemia-initiating cells in B-cell precursor acute lymphoblastic leukemia have not yet been phenotypically identified. Different subpopulations, as defined by surface markers, have shown equal abilities to reconstitute leuke...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058781/ https://www.ncbi.nlm.nih.gov/pubmed/29519870 http://dx.doi.org/10.3324/haematol.2017.167502 |