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Leukemia reconstitution in vivo is driven by cells in early cell cycle and low metabolic state

In contrast to well-established hierarchical concepts of tumor stem cells, leukemia-initiating cells in B-cell precursor acute lymphoblastic leukemia have not yet been phenotypically identified. Different subpopulations, as defined by surface markers, have shown equal abilities to reconstitute leuke...

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Detalles Bibliográficos
Autores principales: Trentin, Luca, Queudeville, Manon, Eckhoff, Sarah Mirjam, Hasan, Nabiul, Münch, Vera, Boldrin, Elena, Seyfried, Felix, Enzenmüller, Stefanie, Debatin, Klaus-Michael, Meyer, Lüder Hinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058781/
https://www.ncbi.nlm.nih.gov/pubmed/29519870
http://dx.doi.org/10.3324/haematol.2017.167502