Structural and cellular mechanisms of peptidyl-prolyl isomerase Pin1-mediated enhancement of Tissue Factor gene expression, protein half-life, and pro-coagulant activity

Tissue Factor is a cell-surface glycoprotein expressed in various cells of the vasculature and is the principal regulator of the blood coagulation cascade and hemostasis. Notably, aberrant expression of Tissue Factor is associated with cardiovascular pathologies such as atherosclerosis and thrombosi...

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Detalles Bibliográficos
Autores principales: Kurakula, Kondababu, Koenis, Duco S., Herzik, Mark A., Liu, Yanyun, Craft, John W., van Loenen, Pieter B., Vos, Mariska, Tran, M. Khang, Versteeg, Henri H., Goumans, Marie-José T.H., Ruf, Wolfram, de Vries, Carlie J.M., Şen, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058786/
https://www.ncbi.nlm.nih.gov/pubmed/29545340
http://dx.doi.org/10.3324/haematol.2017.183087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058786/
https://www.ncbi.nlm.nih.gov/pubmed/29545340
http://dx.doi.org/10.3324/haematol.2017.183087

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