Potentiation of Insulin Signaling Contributes to Heart Failure in Type 2 Diabetes: A Hypothesis Supported by Both Mechanistic Studies and Clinical Trials

The heightened risk of heart failure in type 2 diabetes cannot be explained by the occurrence of clinically overt myocardial ischemic events or hyperglycemia. Experimentally, insulin exerts detrimental effects on the heart, vasculature, kidneys, and adipose tissue that can lead to heart failure. In...

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Detalles Bibliográficos
Autor principal: Packer, Milton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
TRANSLATIONAL PERSPECTIVE
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058949/
https://www.ncbi.nlm.nih.gov/pubmed/30062227
http://dx.doi.org/10.1016/j.jacbts.2018.04.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058949/
https://www.ncbi.nlm.nih.gov/pubmed/30062227
http://dx.doi.org/10.1016/j.jacbts.2018.04.003

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