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In Vivo Reactive Oxygen Species Detection With a Novel Positron Emission Tomography Tracer, (18)F-DHMT, Allows for Early Detection of Anthracycline-Induced Cardiotoxicity in Rodents

Reactive oxygen species (ROS) are involved in doxorubicin-induced cardiotoxicity. The authors investigated the efficacy of (18)F-DHMT, a marker of ROS, for early detection of doxorubicin-induced cardiotoxicity in rats. Echocardiography was performed at baseline and 4, 6, and 8 weeks post-doxorubicin...

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Detalles Bibliográficos
Autores principales: Boutagy, Nabil E., Wu, Jing, Cai, Zhengxi, Zhang, Wenjie, Booth, Carmen J., Kyriakides, Tassos C., Pfau, Daniel, Mulnix, Tim, Liu, Zhao, Miller, Edward J., Young, Lawrence H., Carson, Richard E., Huang, Yiyun, Liu, Chi, Sinusas, Albert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058999/
https://www.ncbi.nlm.nih.gov/pubmed/30062224
http://dx.doi.org/10.1016/j.jacbts.2018.02.003