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Aged Human Multipotent Mesenchymal Stromal Cells Can Be Rejuvenated by Neuron-Derived Neurotrophic Factor and Improve Heart Function After Injury

Reduced regenerative capacity of aged stem cells hampers the benefits of autologous cell therapy for cardiac regeneration. This study investigated whether neuron-derived neurotrophic factor (NDNF) could rejuvenate aged human bone marrow (hBM)- multipotent mesenchymal stromal cells (MSCs) and whether...

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Detalles Bibliográficos
Autores principales: Song, Hui-Fang, He, Sheng, Li, Shu-Hong, Yin, Wen-Juan, Wu, Jun, Guo, Jian, Shao, Zheng-Bo, Zhai, Xiao-Yan, Gong, Hui, Lu, Li, Wei, Fang, Weisel, Richard D., Xie, Jun, Li, Ren-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059002/
https://www.ncbi.nlm.nih.gov/pubmed/30062183
http://dx.doi.org/10.1016/j.jacbts.2017.07.014