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Characterization of TRKA signaling in acute myeloid leukemia

Tropomyosin-related kinase A (TRKA) translocations have oncogenic potential and have been found in rare cases of solid tumors. Accumulating evidence indicates that TRKA and its ligand, nerve growth factor (NGF), may play a role in normal hematopoiesis and may be deregulated in leukemogenesis. Here,...

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Detalles Bibliográficos
Autores principales: Herbrich, Shelley M., Kannan, Sankaranarayanan, Nolo, Riitta M., Hornbaker, Marisa, Chandra, Joya, Zweidler-McKay, Patrick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059018/
https://www.ncbi.nlm.nih.gov/pubmed/30046390
http://dx.doi.org/10.18632/oncotarget.25723