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Identification of integrin drug targets for 17 solid tumor types

Integrins are contributors to remodeling of the extracellular matrix and cell migration. Integrins participate in the assembly of the actin cytoskeleton, regulate growth factor signaling pathways, cell proliferation, and control cell motility. In solid tumors, integrins are involved in promoting met...

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Detalles Bibliográficos
Autores principales: Arun, Adith S., Tepper, Clifford G., Lam, Kit S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059022/
https://www.ncbi.nlm.nih.gov/pubmed/30046394
http://dx.doi.org/10.18632/oncotarget.25731