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Identification of integrin drug targets for 17 solid tumor types
Integrins are contributors to remodeling of the extracellular matrix and cell migration. Integrins participate in the assembly of the actin cytoskeleton, regulate growth factor signaling pathways, cell proliferation, and control cell motility. In solid tumors, integrins are involved in promoting met...
Autores principales: | Arun, Adith S., Tepper, Clifford G., Lam, Kit S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059022/ https://www.ncbi.nlm.nih.gov/pubmed/30046394 http://dx.doi.org/10.18632/oncotarget.25731 |
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