Engineered Functional Redundancy Relaxes Selective Constraints upon Endogenous Genes in Viral RNA Genomes

Functional redundancy, understood as the functional overlap of different genes, is a double-edge sword. At the one side, it is thought to serve as a robustness mechanism that buffers the deleterious effect of mutations hitting one of the redundant copies, thus resulting in pseudogenization. At the o...

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Detalles Bibliográficos
Autores principales: Ambrós, Silvia, de la Iglesia, Francisca, Rosario, Sttefany M, Butković, Anamarija, Elena, Santiago F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059116/
https://www.ncbi.nlm.nih.gov/pubmed/29982435
http://dx.doi.org/10.1093/gbe/evy141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059116/
https://www.ncbi.nlm.nih.gov/pubmed/29982435
http://dx.doi.org/10.1093/gbe/evy141

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