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Positive selection on schizophrenia-associated ST8SIA2 gene in post-glacial Asia

A number of loci are associated with highly heritable schizophrenia and the prevalence of this mental illness has had considerable negative fitness effects on human populations. Here we focused on one particular schizophrenia-associated gene that encodes a sialyltransferase (ST8SIA2) and is expresse...

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Detalles Bibliográficos
Autores principales: Fujito, Naoko T., Satta, Yoko, Hane, Masaya, Matsui, Atsushi, Yashima, Kenta, Kitajima, Ken, Sato, Chihiro, Takahata, Naoyuki, Hayakawa, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059407/
https://www.ncbi.nlm.nih.gov/pubmed/30044798
http://dx.doi.org/10.1371/journal.pone.0200278