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Crystal structures of human procathepsin H

Cathepsin H is a member of the papain superfamily of lysosomal cysteine proteases. It is the only known aminopeptidase in the family and is reported to be involved in cancer and other major diseases. Like many other proteases, it is synthesized as an inactive proenzyme. Although the crystal structur...

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Detalles Bibliográficos
Autores principales: Hao, Yue, Purtha, Whitney, Cortesio, Christa, Rui, Huan, Gu, Yan, Chen, Hao, Sickmier, E. Allen, Manzanillo, Paolo, Huang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059440/
https://www.ncbi.nlm.nih.gov/pubmed/30044821
http://dx.doi.org/10.1371/journal.pone.0200374