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Crystal structures of human procathepsin H
Cathepsin H is a member of the papain superfamily of lysosomal cysteine proteases. It is the only known aminopeptidase in the family and is reported to be involved in cancer and other major diseases. Like many other proteases, it is synthesized as an inactive proenzyme. Although the crystal structur...
Autores principales: | Hao, Yue, Purtha, Whitney, Cortesio, Christa, Rui, Huan, Gu, Yan, Chen, Hao, Sickmier, E. Allen, Manzanillo, Paolo, Huang, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059440/ https://www.ncbi.nlm.nih.gov/pubmed/30044821 http://dx.doi.org/10.1371/journal.pone.0200374 |
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