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IL-27 regulates the number, function and cytotoxic program of antiviral CD4 T cells and promotes cytomegalovirus persistence

The role of IL-27 in antiviral immunity is still incompletely understood, especially in the context of chronic viruses that induce a unique environment in their infected host. Cytomegalovirus (CMV) establishes a persistent, tissue localized infection followed by lifelong latency. CMV infects the maj...

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Detalles Bibliográficos
Autores principales: Wehrens, Ellen J., Wong, Kurt A., Gupta, Ankan, Khan, Ayesha, Benedict, Chris A., Zuniga, Elina I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059457/
https://www.ncbi.nlm.nih.gov/pubmed/30044874
http://dx.doi.org/10.1371/journal.pone.0201249