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Specific inhibitor of Notch-3 enhances the sensitivity of NSCLC cells to gemcitabine

Notch-3 is a receptor of the Notch signaling pathway and plays an important role in regulating self-renewal, differentiation and apoptosis in cancer cells. Overexpression of Notch-3 has been proved to be associated with resistance to gemcitabine (GEM) and poor patient prognosis for various malignant...

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Detalles Bibliográficos
Autores principales: Hu, Bi-Dan, Guo, Jia, Ye, Yuan-Zi, Du, Ting, Cheng, Chun-Song, Jiang, Qian, Liu, Ruo-Nan, Zhang, Yan-Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059738/
https://www.ncbi.nlm.nih.gov/pubmed/29781034
http://dx.doi.org/10.3892/or.2018.6448