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Specific inhibitor of Notch-3 enhances the sensitivity of NSCLC cells to gemcitabine
Notch-3 is a receptor of the Notch signaling pathway and plays an important role in regulating self-renewal, differentiation and apoptosis in cancer cells. Overexpression of Notch-3 has been proved to be associated with resistance to gemcitabine (GEM) and poor patient prognosis for various malignant...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059738/ https://www.ncbi.nlm.nih.gov/pubmed/29781034 http://dx.doi.org/10.3892/or.2018.6448 |