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Multifaceted regulation and functions of YAP/TAZ in tumors

The Hippo pathway, initially identified through screenings for mutant tumor suppressors in Drosophila, is an evolutionarily conserved signaling pathway that controls organ size by regulating cell proliferation and apoptosis. Abnormal regulation of the Hippo pathway may lead to cancer in mammals. As...

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Detalles Bibliográficos
Autores principales: Liu, Huirong, Du, Suya, Lei, Tiantian, Wang, Hailian, He, Xia, Tong, Rongsheng, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059739/
https://www.ncbi.nlm.nih.gov/pubmed/29749524
http://dx.doi.org/10.3892/or.2018.6423