Local immunomodulation with Fas ligand-engineered biomaterials achieves allogeneic islet graft acceptance

Islet transplantation is a promising therapy for type 1 diabetes. However, chronic immunosuppression to control rejection of allogeneic islets induces morbidities and impairs islet function. T-effector cells are responsible for islet allograft rejection and express Fas death receptor following activ...

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Detalles Bibliográficos
Autores principales: Headen, Devon M., Woodward, Kyle B., Coronel, María M., Shrestha, Pradeep, Weaver, Jessica D., Zhao, Hong, Tan, Min, Hunckler, Michael D., Bowen, William S., Johnson, Christopher T., Shea, Lonnie, Yolcu, Esma S., García, Andrés J., Shirwan, Haval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060019/
https://www.ncbi.nlm.nih.gov/pubmed/29867165
http://dx.doi.org/10.1038/s41563-018-0099-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060019/
https://www.ncbi.nlm.nih.gov/pubmed/29867165
http://dx.doi.org/10.1038/s41563-018-0099-0

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