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Skeletal muscle autophagy remains responsive to hyperinsulinemia and hyperglycemia at higher plasma insulin concentrations in insulin‐resistant mice

Skeletal muscle autophagy is suppressed by insulin, but it is not clear if such suppression is altered with insulin resistance. We investigated if the inhibitory action of insulin on autophagy remains intact despite insulin resistance to glucose metabolism. C57BL/6J mice consumed either a low‐fat (1...

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Detalles Bibliográficos
Autores principales: Ehrlicher, Sarah E., Stierwalt, Harrison D., Newsom, Sean A., Robinson, Matthew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060106/
https://www.ncbi.nlm.nih.gov/pubmed/30047243
http://dx.doi.org/10.14814/phy2.13810