Autophagic cell death participates in POMC-induced melanoma suppression

Hypoxia in tumors is known to trigger the pro-survival pathways such as autophagy. Systemic proopiomelanocortin (POMC) gene therapy suppresses melanoma through apoptosis induction and neovascularization blockage. In this study, we investigated the crosstalk between autophagic and apoptotic signaling...

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Detalles Bibliográficos
Autores principales: Wu, Jian-Ching, Tsai, Han-En, Liu, Guei-Sheung, Wu, Chieh-Shan, Tai, Ming-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060113/
https://www.ncbi.nlm.nih.gov/pubmed/30062060
http://dx.doi.org/10.1038/s41420-018-0070-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060113/
https://www.ncbi.nlm.nih.gov/pubmed/30062060
http://dx.doi.org/10.1038/s41420-018-0070-5

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