Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone loss

Receptor activator of NFkB ligand (RANKL) is a TNF-family cytokine required for osteoclast formation, as well as immune cell and mammary gland development. It is produced as a membrane-bound protein that can be shed to form a soluble protein. We created mice harboring a sheddase-resistant form of RA...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiong, Jinhu, Cawley, Keisha, Piemontese, Marilina, Fujiwara, Yuko, Zhao, Haibo, Goellner, Joseph J., O’Brien, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060116/
https://www.ncbi.nlm.nih.gov/pubmed/30046091
http://dx.doi.org/10.1038/s41467-018-05244-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060116/
https://www.ncbi.nlm.nih.gov/pubmed/30046091
http://dx.doi.org/10.1038/s41467-018-05244-y

Ejemplares similares